Vardenafil, sold under the brand name Levitra among others, is a medication that is used for treating erectile dysfunction.
- Vardenafil is available by prescription only.
- Common side effects include headache and flushing.
- It should be taken on an empty stomach for best results.
- Do not combine vardenafil with nitrates.
Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's. Despite the structural differences between vardenafil and sildenafil, they both show similar ocular side effects due to their similar selectivity overlap with PDE6, an enzyme found in the eye.
How to save on vardenafil
But if you have severe kidney disease, your prescriber may suggest an alternative to vardenafil. It’s also recommended that people receiving dialysis avoid this medication. Vardenafil hasn’t been well studied for safety or effectiveness in this population. Your liver helps metabolize (break down) vardenafil. Similar to the kidneys, if your liver isn’t working well, vardenafil can build up.
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The recommended vardenafil dosages for liver disease depend on how severe the condition is: Mild liver disease: Follow the typical vardenafil dosages as described above. Mild liver disease: Follow the typical vardenafil dosages as described above. Moderate liver disease: The starting dosage is 5 mg about 1 hour before sex. This can be raised to a maximum of 10 mg. Severe liver disease: It’s not recommended to take vardenafil if you have severe liver disease. Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from penetration to ejaculation. The common, adverse drug reactions (side effects) are the same as with other PDE5 inhibitors. The frequent vardenafil-specific side-effect is nausea; the infrequent side effects are abdominal pain, back pain, vardenafil pills photosensitivity, abnormal vision, eye pain, facial edema, hypotension, palpitation, tachycardia, arthralgia, myalgia, rash, itch, and priapism. One possibly serious, but rare, side effect with vardenafil is heart attack.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 150mg | 60 + 4 Pills | 111.25€ 105.95€ | |
| Levitra Generic | 20mg | 60 + 6 Pills | 131.11€ 124.87€ | |
| Levitra Generic | 20mg | 20 Pills | 52.63€ 50.12€ | |
| Kamagra Polo | 100mg | 12 Pills | 60.21€ 57.34€ | |
| Levitra Original | 20mg | 12 Pills | 81.99€ 78.09€ | |
| Levitra Generic | 40mg | 90 + 6 Pills | 234.73€ 223.55€ | |
| Kamagra Gold | 100 mg | 32 Pills | 121.24€ 115.47€ | |
| Cialis Original | 20mg | 22 + 2 Pills | 129.20€ 123.05€ | |
| Cialis Original | 20mg | 48 + 4 Pills | 224.69€ 213.99€ | |
| Cialis Soft Tabs | 20mg | 30 + 4 Pills | 87.43€ 83.27€ | |
| Kamagra Gold | 100 mg | 60 + 4 Pills | 201.34€ 191.75€ | |
| Levitra Generic | 10mg | 270 + 10 Pills | 338.09€ 321.99€ |
Also, in rare cases, vardenafil use may cause priapism, a very painful emergency condition that can cause impotence if left untreated. In October 2007, the U.S. Food and Drug Administration (FDA) announced that a warning about possible deafness (sudden hearing loss) would be added to the drug labels of vardenafil, and other PDE5 inhibitors. Vardenafil should not be used by people taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
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But if anything seems severe or life threatening, call 911 or go to the nearest ER. There are ways to save on vardenafil, which is only available as a generic medication. GoodRx can help you save over 80% off the average retail price of the generic version. The price for five of the 10 mg vardenafil tablets at certain pharmacies is as low as $25.04 with a free GoodRx discount. The typical starting vardenafil dosage for erectile dysfunction is 10 mg by mouth about 1 hour before sex.
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If needed, your dosage can be raised up to a maximum of 20 mg per day. You should only take vardenafil once a day, regardless of what dose you’ve been prescribed. Adults ages 65 and older may need to take a lower vardenafil dosage to reduce the risk of side effects. The same can be said for people with liver disease or if you take certain interacting medications. Your prescriber can help you figure out the best vardenafil dosage for you. Further, vardenafil causes lengthening of the QT interval. Therefore, it should not be taken by people taking other medications that affect the QT interval (such as amiodarone). Vardenafil was co-marketed by Bayer Pharmaceuticals, GlaxoSmithKline, and Schering-Plough under the brand name Levitra. As of 2005, the co-promotion rights of GSK on Levitra have been returned to Bayer in many markets outside the US. Thus, because of European Union trade rules, parallel imports might result in Vivanza sold next to Levitra in the EU. An orally disintegrating form, marketed as Staxyn and Levitra Soft, has been gaining approvals in countries such as the United States[11] and Canada. The US Food and Drug Administration (FDA) has found vardenafil and other synthetic PDE5 inhibitors in numerous products marketed as "herbal" supplements or "all natural" products for male enhancement. ^ a b c d "Levitra (vardenafil hydrochloride) tablets, for oral use Initial U.S. Approval: 2003".
7.2 Effect of Other Drugs on Vardenafil
In many cases, lowering your vardenafil dosage can cenforce 200 uk help manage these interactions. Vardenafil’s labeling gives specific dosage adjustments for certain interactions, as detailed in the table below. This is not a complete list of vardenafil interactions. You should share an up-to-date medication list with your prescriber and pharmacist. This can help them check for potential interactions.
How should I store vardenafil?
Taking too much vardenafil may raise your risk of side effects, such as headache or back pain. Some people have reported temporary vision problems after taking more vardenafil than recommended. But certain side effects could become dangerous, such as low blood pressure which could cause you to feel dizzy or faint. If you’ve taken too much vardenafil, contact your prescriber for guidance. You can also call Poison Control at 1-800-222-1222. ^ "Levitra (Vardenafil) is A Drug Used to Treat Erectile Problems in Men" (in German). "Potency, selectivity, and consequences of nonselectivity of PDE inhibition". "Effects of vardenafil administration on intravaginal ejaculatory latency time in men with lifelong premature ejaculation". "Counseling Patients About Sexual Issues: Drug-Induced Priapism". ^ "FDA Announces Revisions to Labels for Cialis, Levitra and Viagra". Archived from the original on July 9, 2009. "Pharmacology and drug interaction effects of the phosphodiesterase 5 inhibitors: focus on alpha-blocker interactions". "The QT Interval and Selection of Alpha-Blockers for Benign Prostatic Hyperplasia". ^ "New erectile dysfunction treatment Staxyn approved in the U.S. - Pharmaceutical Processing".
Proper Use
So you should take your doses shortly before you plan to have sex. In this guide, we’ll discuss more details about typical vardenafil dosages. This includes the recommended starting dose and when adjustments may be needed. The typical starting vardenafil dosage is 10 mg by mouth about 1 hour before sexual activity. Depending on how effective it is and whether you have side effects, your prescriber may adjust this dose to anywhere between 5 mg and 20 mg (the maximum dose).
Usual Adult Dose for:
Don’t take vardenafil more than once a day, regardless of which dose you’ve been prescribed. Vardenafil comes as both a traditional tablet and an orally disintegrating tablet (ODT). If you’re taking the ODT, place the tablet on your tongue. You shouldn’t drink water while the tablet is dissolving. Depending on your age and medical history, you may need to take a lower vardenafil dosage. Archived from sex power tablet the original on April 6, 2012. ^ "Staxyn - New Innovation in Erectile Dysfunction Helps Younger Men Rise to the Occasion". U.S. Food and Drug Administration (FDA). ^ Tucker J, Fischer T, Upjohn L, Mazzera D, Kumar M (October 2018). "Unapproved Pharmaceutical Ingredients Included in Dietary Supplements Associated With US Food and Drug Administration Warnings". Vardenafil is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men.
- Vardenafil is effective for up to 4-5 hours.
- Do not use if allergic to vardenafil or similar drugs.
- Overdose symptoms may include prolonged erections.
- Medical advice is essential for any severe side effects.
Vardenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Vardenafil does not cure erectile dysfunction or increase sexual desire.
What should you do if you take too much vardenafil?
This is also true if you take certain medications that interact with vardenafil. These dosage adjustments help to lower the risk of side effects from vardenafil. Your prescriber will be in charge of determining whether you should take a different vardenafil dosage. You shouldn’t try to adjust your dosage on your own. Adults ages 65 and older tend to have higher amounts of vardenafil in their bloodstream after a dose than younger adults (even if they take the same dose).
What are some other side effects of this drug?
This means older adults may have a greater risk or be more sensitive to side effects. If you’re 65 or older, it’s recommended to lower the starting vardenafil dosage to 5 mg and slowly raise it if needed. The kidneys help clear vardenafil from the body. If your kidneys aren’t working as expected, vardenafil can build up and cause side effects. If you have mild to moderate kidney disease, you’ll likely take the standard vardenafil dosage as discussed above. Vardenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Vardenafil comes as a tablet and a rapidly disintegrating (dissolves in the mouth and is swallowed without water) tablet to take by mouth.
- Vardenafil efficacy depends on proper dosage and timing.
- It is generally safe when used as directed.
- Patients should avoid heavy meals before intake.
- Follow-up with your healthcare provider regularly.
It is usually taken as needed, with or without food, 60 minutes before sexual activity.
| Dosage (mg) | Typical Usage | Onset of Action | Duration of Effect |
|---|---|---|---|
| 10 | Mild to moderate ED | 30-60 minutes | Up to 4 hours |
| 20 | Moderate to severe ED | 30-60 minutes | Up to 4-5 hours |
| 5 | Lower dose for less side effects | 30-60 minutes | Up to 4 hours |
| 25 | Off-label use, clinical trials | 30-60 minutes | Up to 4 hours |
Vardenafil usually should not be taken more often than once every 24 hours. If you have certain health conditions or are taking certain medications, your doctor may tell you to take vardenafil less often. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor. If you are taking the rapidly disintegrating tablet, check the blister pack before you take your first dose. Do not use any of the medication from the pack if any of the blisters are torn, broken, or do not contain tablets.
