Long-Term Use Considerations for Both Medications

If you have ever had an allergic reaction to a medicine. If you are taking any viagra sildenafil price other medicines. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack.

What other medications affect dapoxetine (Priligy)?

(2014) Results from a prospective observational study of men with premature ejaculation treated with dapoxetine or alternative care: The PAUSE study. (2013) Dapoxetine treatment in patients with lifelong premature ejaculation: the reasons of a 'Waterloo'. (2006) Efficacy and tolerability of dapoxetine in treatment of premature ejaculation: an integrated analysis of two double-blind, randomized controlled trials Lancet 368: 929–37 The integrated process statement sets out the process NICE uses to select topics for the evidence summaries: new medicines and how the summaries are developed, quality assured and approved for publication. Ian Pearce, Consultant Urological Surgeon, Honorary Senior Lecturer, University of Manchester, Manchester Royal Infirmary Mike Foster, Consultant Urologist, Heart of England NHS Trust Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 14 Apr 2025 Dapoxetine is prescribed for the treatment of premature ejaculation. Take one tablet 1-3 hours viagra daily before you have sex.

Key Differences Between Priligy and Viagra

The most common side-effects include feeling dizzy or faint, and feeling sick (nausea). Drinking a full glass of water at the same time as taking the tablet can reduce these effects. Premature ejaculation is the term used when a man orgasms (ejaculates) more quickly than he and/or his partner would like. For some men it can be temporary and can get better on its own; for others, prescribed treatments such as dapoxetine tablets can be helpful. Dapoxetine is a selective serotonin reuptake inhibitor medicine which has been specially developed for the treatment of premature ejaculation.

Important information about all medicines

It increases the time it takes to ejaculate and can improve the control over the ejaculation. It starts to work very quickly, so it is taken when you anticipate having sex, rather than every day. You have to take it 1-3 hours before you have sex. Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking dapoxetine it is important that your doctor knows: If you have a tendency to faint. It will give you more information about dapoxetine, and will also provide you with a full list of the side-effects which you could experience from taking it.

Product	Dosage	Quantity + Bonus	Price
Viagra Generic	50mg	60 + 4 Pills	83.93€ 79.93€	Buy
Viagra Super Active	100mg	20 + 4 Pills	48.05€ 45.76€	Buy
Viagra Generic	25mg	180 + 6 Pills	154.93€ 147.55€	Buy
Viagra Generic	50mg	30 + 4 Pills	54.26€ 51.68€	Buy
Viagra Original	100mg	120 + 8 Pills	470.39€ 447.99€	Buy
Viagra Generic	200mg	360 + 10 Pills	481.98€ 459.03€	Buy
Viagra Generic	50mg	270 + 8 Pills	198.48€ 189.03€	Buy
Viagra Professional	100mg	270 + 6 Pills	456.97€ 435.21€	Buy
Viagra Generic	25mg	30 + 4 Pills	47.97€ 45.69€	Buy
Viagra Original	100mg	8 Pills	59.84€ 56.99€	Buy
Viagra Generic	150mg	30 + 2 Pills	72.32€ 68.88€	Buy
Viagra Generic	200mg	90 + 6 Pills	170.79€ 162.66€	Buy
Viagra Original	100mg	48 + 4 Pills	207.15€ 197.29€	Buy
Viagra Soft Tabs	100mg	120 + 8 Pills	232.21€ 221.15€	Buy

Take dapoxetine exactly as your doctor tells you to.

What is the satisfaction rate with dapoxetine?

If dapoxetine is continued, the benefit/risk balance should be re-evaluated at least every 6 months. Consideration will need to be given to how treatment efficacy can be assessed given the subjective nature of efficacy outcomes. Premature ejaculation can occur in conjunction with erectile dysfunction and the European Association of Urology 2014 guidelines on male sexual dysfunction states that if premature ejaculation is secondary to erectile dysfunction then the erectile dysfunction should be treated before or at the same time as the premature ejaculation. It should be noted however, that the summary of product characteristics states that dapoxetine should not be used in men taking phosphodiesterase type 5 inhibitors (for example, sildenafil) as this increases the risk of syncope. For a number of men pharmacological treatment of premature ejaculation will not be acceptable.

Redefining a sexual medicine paradigm: subclinical premature ejaculation as a new taxonomic entity

A prospective observational study from a single clinical centre in Italy (Mondaini et al. 2013) assessed the acceptance and discontinuation rates of 'on demand' dapoxetine 30 mg (titrated to 60 mg after 3 months if low efficacy) in 120 men with lifelong premature ejaculation. Twenty-four (20%) of the men decided not to start dapoxetine. Fear of using a 'drug' was the most frequently reported reason for treatment non-acceptance (50%). In addition, the majority of men who took dapoxetine discontinued treatment.

What Is the Role of Ejaculation Latency in the Diagnosis of Premature Ejaculation and Does the Ejaculation Latency Threshold Matter?

The main reasons for treatment discontinuation were efficacy below expectations, side effects and costs. Out of the 96 men who decided to start dapoxetine, only 10 men were continuing the treatment after 1 year. Dapoxetine is the only medicine licensed in the UK for the treatment of premature ejaculation, although other treatments are used off-label for this indication. The General Medical Council advice to use a licensed medicine whenever possible should be taken into consideration. The manufacturer has estimated that based on a GP-registered population of 100,000 people, 5851 men aged 18 to 64 will be affected by premature ejaculation with 1151 men severely affected (A. Drink a full glass of water at the same time as you take a tablet. The recommended starting dose is one 30 mg tablet, taken 1 to 3 hours before you anticipate having sex. Your doctor may later decide to increase your dose to one 60 mg tablet. Your doctor will only prescribe the higher dose for you if the 30 mg dose is insufficient, and providing you have not experienced any side-effects such as feeling faint. Do not take more than one tablet in any 24 hours. Dapoxetine is not intended for regular daily use - you should only take it before you anticipate having sex.

• Priligy has a quick onset but short duration.
• Viagra's typical dose is 50 mg but varies.
• Timing of administration affects drug efficacy.

The tablet has a bitter taste, so swallow it whole without chewing. You can take it either with or without food. Make sure you keep your follow-on appointments with your doctor. This is so your doctor can check on your progress. Do not drink alcohol whilst taking dapoxetine, as it might increase the sedative effects of the alcohol. It can also increase the risk of fainting. Do not use any recreational drugs while you are taking dapoxetine, as this could lead to you experiencing serious side-effects. A chemical in grapefruit juice can increase the amount of dapoxetine in your bloodstream and this increases the risk of side-effects.

Medication	Active Ingredient	Dosage Forms	Onset Time	Duration of Action
Priligy	Dapoxetine	Tablets (30mg/60mg)	1-3 hours	4-6 hours
Viagra	Sildenafil	Tablets (50mg/100mg)	30-60 mins	4-6 hours
Cialis	Tadalafil	Tablets (10mg/20mg)	30 mins	Up to 36 hours
Levitra	Vardenafil	Tablets (10mg)	25-60 mins	About 4-5 hours

If you do drink grapefruit juice, do not take a dapoxetine tablet for at least 24 hours afterwards. Take care if you are a driver. If you feel faint or dizzy, do not drive and do not use tools or machines.

Aspect	Priligy (Dapoxetine)	Viagra (Sildenafil)	Combined Use Effectiveness
Effectiveness in delaying ejaculation	High (80-90%)	Not relevant	Variable, depends on individual response
Improvement in erectile function	No	Yes	Yes, when used with ED indication
Satisfaction rate in users	70-80%	75-85%	Enhanced with proper management
Onset of noticeable effects	1-3 hours	30-60 mins	Typically within 30 minutes to 2 hours

If you buy any medicines, please check with your doctor or a pharmacist that they are suitable for you to take with dapoxetine.

Interaction Type	Priligy (Dapoxetine)	Viagra (Sildenafil)
Other serotonergic drugs	Increased risk of serotonin syndrome	Not relevant
CYP3A4 inhibitors	Increased dapoxetine levels	May increase sildenafil levels
Nitrates	Contraindicated	Contraindicated
Alcohol	Can increase side effects	Can cause hypotension, dizziness

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them.

How long does dapoxetine make me last?

Menarini Farmaceutica Internazionale: personal communication January 2014). The manufacturer further estimates that 25% of the men severely affected by premature ejaculation will seek treatment and 70% of those seeking treatment could be prescribed dapoxetine. The manufacturer therefore estimates that based on a GP-registered population of 100,000, 202 men aged 18 to 64 may potentially be prescribed dapoxetine over a 5-year period (A. Menarini Farmaceutica Internazionale: personal communication January 2014). The manufacturer estimated that in 2013 approximately 75% of European sales of dapoxetine were for the 30 mg strength.

Can You Buy Priligy and Viagra as a Combination Pill?

Dapoxetine for premature ejaculation was not considered appropriate for a NICE technology appraisal and is not currently planned into any other work programme. There is no NICE guidance on premature ejaculation. A. Menarini Farmaceutica Internazionale (2013) Priligy 30 mg and 60 mg film-coated tablets summary of product characteristics [online; accessed 12 March 2014] Buvat J, Tesfaye F, Rothman M et al. (2009) Dapoxetine for the treatment of premature ejaculation: results from a randomized, double-blind, placebo-controlled phase 3 trial in 22 countries.

Will modafinil interact with Viagra if I take them together?

European Association of Urology (2014) Guidelines on male sexual dysfunction [online; accessed 11 April 2014] Kaufman JM, Rosen RC, Mudumbi RV et al. (2009) Treatment benefit of dapoxetine for premature ejaculation: results from a placebo-controlled phase III trial. (2010) Treatment of premature ejaculation in the Asia-Pacific region: results from a phase III double-blind, parallel-group study of dapoxetine. The Journal of Sexual Medicine 7: 256–68 McMahon CG, Althof SE, Kaufman JM et al. (2011) Efficacy and safety of dapoxetine for the treatment of premature ejaculation: integrated analysis of results from five phase 3 trials. The table below contains some of the most common ones associated with dapoxetine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. If you experience any other symptoms which you think may be due to the tablets and which you are concerned about, speak with your doctor or pharmacist for advice. Keep all medicines out of the reach and sight of children. Store in a cool, dry place, away from direct heat and light.

Treating ED and PE at the same time

If you have a tendency to faint. If you have a bleeding or clotting disorder. If you have ever had a mental health problem causing 'high' or 'low' moods, such as bipolar disorder, depression or mania. If you have increased pressure in your eye, a condition called glaucoma. If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work. Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty. Never give it to other people even if their condition appears to be the same as yours. If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment which medicines you are taking. Do not keep out-of-date or unwanted medicines.

• Priligy (Dapoxetine) is used to treat premature ejaculation.
• Viagra (Sildenafil) enhances blood flow for erectile dysfunction.
• Both are prescription medications for male sexual health.

Take them to your local pharmacy which will dispose of them for you. If you have any questions about this medicine ask your pharmacist. If you experience side effects, you can report them online through the Yellow Card website.

• Common Priligy side effects include nausea and dizziness.
• Viagra may cause headaches and visual disturbances.
• Serious risks include priapism and allergic reactions.