Its safety in women has not been established.
| Parameter | Value | Details |
|---|---|---|
| Absorption | Rapid | Peak plasma at 1-2 hours |
| Bioavailability | Approximately 64% | Oral administration |
| Half-life | 12-13 hours | Duration of action |
| Metabolism | Liver via CYP3A4 enzymes | Hepatic pathways |
Do not take PRILIGY if you are under 18 years of age, or over 65 years of age.
- The usual starting dose of dapoxetine is 30mg, increased to 60mg if needed.
- 30mg tablets come in film-coated forms for easier swallowing.
- The drug is contraindicated in patients with hypersensitivity to dapoxetine.
- No significant effect on fertility or long-term sexual function reported.
- Clinical trials indicate improvement in intravaginal ejaculatory latency time.
- Avoid grapefruit juice as it can interfere with dapoxetine metabolism.
- Emergency contraception is unrelated and should be discussed separately.
- Usage should be disclosed before surgical procedures due to interaction risk.
Safety and effectiveness in patients under 18 years or over 65 years have not been established.
- The medication should be part of a treatment plan.
- The plan includes follow-up, dose adjustment, and support.
- Treatment success is not solely defined by time.
- Improved perceived control and satisfaction are key.
- Partners may be included in counseling sessions.
- Communication skills are often addressed.
- Sensate focus exercises may be recommended.
- The drug can provide a "window of opportunity" for therapy.
- Some men may eventually discontinue medication.
- Others may require long-term intermittent use.
- There is no defined maximum duration of use.
- Annual review of continued need is prudent.
This medicine contains lactose (a type of sugar).
| Interacting Drug/Class | Effect on Dapoxetine | Potential Risk |
|---|---|---|
| CYP3A4 inhibitors | Increased plasma levels | Greater side effect risk |
| SSRIs | Serotonin syndrome risk | Use cautiously or avoid combination |
| Alcohol | Increased sedative effects | Impairment and risk of dizziness |
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine. Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop. Some medicines and PRILIGY may interfere with each other.
Regulatory history
Menarini, Thailand; A. Menarini Farmaceutica Internazionale, United Kingdom; A. Menarini New Zealand, New Zealand; A. Menarini Singapore, Vietnam; Berlin-Chemie, Czech Republic; Berlin-Chemie, Germany; Berlin-Chemie, Estonia; Berlin-Chemie, Norway; Berlin-Chemie, Sweden; Janssen-Cilag, Italy; Laboratorios Menarini, Spain; Menarini, Belgium; Menarini, Finland; Menarini, France; Menarini, Georgia; Menarini, Greece; Menarini, Mexico; Menarini, Malaysia; Menarini, Netherlands; Menarini International, Malta; A.Menarini China Holding Co., Ltd., China Priligy 30mgBerlin-Chemie, Austria; Berlin-Chemie, Hungary; Menarini, Switzerland; Menarini, Luxembourg Further information on drug naming conventions: International Nonproprietary Names. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Generic Names
Do not use if you have ever had an allergic reaction to dapoxetine hydrochloride or any of the ingredients listed at the end of the CMI. There are a number of circumstances in which a person should not take this medicine or may need to use caution. It is important to understand if these apply to you before taking PRILIGY. Talk to your doctor or pharmacist if you have any concerns about taking this medicine. The recommended dose is one tablet (30 mg) taken when you need it, about 1 to 3 hours before sexual activity.
Competing interests
Do not take more than one tablet in a 24 hour period. It is not intended for continuous daily use. Swallow the tablet whole with at least one full glass of water. PRILIGY can be taken with or without food. Do not drink grapefruit juice within 24 hour prior to taking PRILIGY. linezolid, an antibiotic used to treat infection tryptophan, used to help your mood and help you sleep St John's wort (Hypericum perforatum), a herbal preparation.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Priligy Generic Dapoxetine | 60mg | 120 + 10 Pills | 341.26€ 325.01€ | |
| Kamagra Polo | 100 mg | 12 Pills | 60.21€ 57.34€ | |
| Tadalista Super Active | 20mg | 120 + 16 Pills | 382.15€ 363.95€ | |
| Priligy Generic Dapoxetine | 60mg | 90 + 10 Pills | 265.64€ 252.99€ | |
| Priligy Generic Dapoxetine | 60mg | 10 Pills | 47.63€ 45.36€ | |
| Viagra Generic | 25mg | 20 Pills | 37.74€ 35.94€ | |
| Viagra Professional | 100mg | 10 Pills | 44.09€ 41.99€ | |
| Priligy Generic Dapoxetine | 60mg | 30 + 6 Pills | 106.65€ 101.57€ | |
| Kamagra 100 mg | 100 mg | 60 + 4 Pills | 201.34€ 191.75€ | |
| Priligy Generic Dapoxetine | 60mg | 60 + 8 Pills | 183.06€ 174.34€ | |
| Priligy Generic Dapoxetine | 60mg | 20 + 4 Pills | 77.31€ 73.63€ | |
| Cialis Generic | 5mg | 120 + 6 Pills | 132.92€ 126.59€ | |
| Kamagra Gold | 100 mg | 12 Pills | 55.64€ 52.99€ | |
| Cialis Super Active | 20mg | 90 + 10 Pills | 314.14€ 299.18€ | |
| Priligy Generic Dapoxetine | 60mg | 180 + 10 Pills | 494.76€ 471.20€ |
PRILIGY should not be taken with the above listed medicines/ herbal preparations or within 14 days of stopping these medicines.
Prescription Required (Rx) to Buy?
you have a history of mania or severe depression. you have heart problems, such as heart failure or problems with dapoxetine sildenafil online the heart rhythm. you have moderate to severe liver problems. you are prone to fainting or passing out caused by a temporary drop in blood pressure (Syncope). Before you start taking this medicine, your doctor should perform a test to make sure that your blood pressure doesn’t drop too much when you stand up from sitting or lying down.
What PRILIGY contains
you have not been diagnosed with premature ejaculation you use recreational drugs such as ecstasy or LSD (lysergic acid diethylamide). Taking PRILIGY with these drugs can cause serious reactions. you take narcotics (strong pain medicines) or benzodiazepines such as Valium. These medicines can increase the drowsiness and dizziness of PRILIGY. Alcohol can increase the risk of fainting and should be avoided while taking PRILIGY.
Foreign Names
you are currently using medications to treat fungal infections you are currently taking medicine that thins your blood such as aspirin, anticoagulants such as warfarin, non-steroidal anti-inflammatory medicines (NSAIDs) such as ibuprofen, or medicine used to treat psychiatric conditions such as depression. Taking PRILIGY together with these medications can increase the risk of bleeding abnormalities. you have a history of dizziness from low blood pressure you have or have had heart and blood vessel problems you have a history of bleeding or blood clotting problems you have or have had any thoughts of suicide or harming yourself. All thoughts of suicide must be taken seriously. Tell your doctor or a mental health professional immediately if you have any suicidal thoughts or other mental/mood changes. Once you stop taking PRILIGY you will need to wait 7 days before taking these medicines/ herbal preparations.
- The recommended dose of dapoxetine for most men is 30mg per tablet.
- If 30mg is not effective, doctors may increase the dose to 60mg.
- Dapoxetine 30mg is not intended for daily use, only on-demand.
- It is not suitable for men with heart problems or low blood pressure.
- Avoid taking other SSRIs or MAO inhibitors while using dapoxetine.
- Dapoxetine 30mg should not be used by individuals under 18 years old.
- Inform your doctor about all medications you're currently taking before use.
- Store the tablets at room temperature, away from moisture and heat.
Other medicines or food and PRILIGY may interfere with each other. medicines for mental health problems other than depression medicines to thin your blood, such as warfarin certain medicines for fungal infections, including ketoconazole, itraconazole and fluconazole certain medicines for HIV, including ritonavir, saquinavir and atazanavir certain medicines used to treat high blood pressure and chest pain (angina), enlarged prostate, or erectile dysfunction (impotence), as these medicines may lower your blood pressure, possibly upon standing anti-inflammatory medicines such as ibuprofen or aspirin certain antibiotics for treating infection, such as erythromycin, telithromycin and clarithromycin Do not drink grapefruit juice within 24 hours prior to taking PRILIGY narcotics (strong pain medicines) or benzodiazepines such as valium.
- The drug is not a hormone and does not affect testosterone.
- It does not cause infertility.
- It is not a contraceptive.
- Sperm parameters are not affected.
- It is safe to conceive a child while using the medication.
- There is no evidence of teratogenicity via semen.
- However, partners who are pregnant or planning should consult a doctor.
- The focus is on improving sexual function and satisfaction.
- Quality of life improvements are documented.
- The Psychological and Interpersonal Relationship Scales can measure this.
- Treatment can reduce anxiety related to performance.
- This reduction in anxiety can itself improve ejaculatory control.
Check with your doctor or pharmacist if you are not sure about what medicines, vitamins or supplements you are taking and if these affect PRILIGY. These medicines may be affected by PRILIGY or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines. Other medicines not listed here may be affected by PRILIGY or may affect how well it works. Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine. The recommended dose is one tablet (30mg), taken when you need it, about 1 to 3 hours before sexual activity.
| Aspect | Description | Notes |
|---|---|---|
| Generic Name | Dapoxetine | Also known as Priligy |
| Dosage | 30 mg per tablet | Usually taken 1-3 hours before activity |
| Formulation | Oral tablet | Available in blister packs |
| Manufacturer | Multiple pharmaceutical companies | Not brand-specific |
Do not take more than one tablet once every 24 hours due to increased risk of side effects and lack of additional benefit.
Further information
you have or have had psychiatric disorders, such as schizophrenia you have history of mania (great excitement, hallucinations, difficulty in concentrating or staying still) or bipolar disorder (extreme mood swings between mania and depression) or develop these disorders you have or have had seizures (fits) or have uncontrolled epilepsy you have moderate or severe liver problems you have or have had other forms of sexual problems such as erectile dysfunction. It is not known whether PRILIGY can worsen these conditions. you have eye problems such as glaucoma, (high pressure in the eye ) During treatment, you may be at risk of developing certain side effects. It is important you understand these risks and how to monitor for them. PRILIGY has been studied for use by men with premature ejaculation. Swallow the tablet whole to avoid a bitter taste, with at least one full glass of water. PRILIGY may be taken with or without food.
See also
Common side effects include nausea; headache; dizziness; fainting or feeling dizzy upon standing; increased blood pressure; flushing; trembling; tingling or numbness; blurred vision, eye pain; ringing in ears; nasal congestion; dry mouth, vomiting, diarrhoea, constipation, abdominal pain, indigestion, intestinal gas, bloating ; excessive sweating; fatigue, sleepiness, yawning; difficulty paying attention, feeling irritable; erectile dysfunction (difficulty getting or keeping an erection); difficulty sleeping; anxiety, nervousness; decreased sexual desire; and abnormal dreams. Serious side effects requiring medical attention include fits (seizures); changes in your mood, thoughts of suicide or harming yourself; an allergic reaction; unusual bruising and bleeding. For more information, including what to do if you have any side effects, see Section This leaflet provides important information about using PRILIGY. You should also speak to your doctor or pharmacist if you would like further information or if you have any concerns or questions about using PRILIGY. Where to find information in this leaflet: PRILIGY contains the active ingredient dapoxetine hydrochloride.
Cardiovascular safety
PRILIGY is a type of drug called a selective serotonin reuptake inhibitor (SSRI) and it is also known as a urological medicine. PRILIGY is a treatment for premature ejaculation (PE) in men 18 to 64 years old who have all of the following: ejaculation in less than 2 minutes following vaginal penetration, on most occasions, with little stimulation and before the man wishes to; and marked personal distress and interpersonal difficulty as a result of premature ejaculation (premature ejaculation troubles the man and his partner); and PRILIGY increases your time to ejaculation and can improve your control over ejaculation and reduce your distress over how fast you ejaculate. This may improve your satisfaction with sexual intercourse. you are allergic to dapoxetine hydrochloride, or any of the ingredients listed at the end of this leaflet. Always check the ingredients to make sure you can take this medicine.
Mechanism of action
you are taking a monoamine oxidase inhibitor (MAOI ) medicine used to treat depression, or have taken a MAOI within the last 14 days (see Section Once you stop taking PRILIGY you will need to wait 7 days before taking a MAOI. you are taking thioridazine used to treat schizophrenia, or have taken thioridazine within the last 14 days. Once you stop taking PRILIGY you will need to wait 7 days before taking thioridazine. you are taking a serotonin reuptake inhibitor (such as a selective serotonin reuptake inhibitor (SSRI), serotonin-norepinephrine reuptake inhibitor (SNRI), tricyclic antidepressant (TCA)), and certain other medicines and herbal products to treat depression or have taken these medicines within the last 14 days (see Section for examples of serotonin reuptake inhibitors and other medicines used to treat depression). Once you stop taking PRILIGY you will need to wait 7 days before taking these medications/herbal products.